In the MPG lab, we pursue a variety of research interests. One of our primary projects investigates how DNA variation can lead to disease, specifically focusing on obesity-related diseases using zebrafish as a model organism. We have successfully established a zebrafish obesity model and are examining the early effects of obesity that may contribute to diseases such as diabetes and non-alcoholic fatty liver disease. Additionally, we explore naturally occurring therapies for drug-resistant breast cancer cells. In our laboratory, we have been able to kill drug-resistant breast cancer cells using substances found in common food items such as herbs, chili peppers, and more recently, algae from Tampa Bay.
Our lab also supports students interested in environmental research. These students have examined differential gene expression in Eastern Oysters based on salinity variations. Another environmental project has investigated the impact of weather and human activities on humpback whale behaviors. Furthermore, we are studying the dangers of disinfectant by-products in drinking water and their links to head and neck cancer and leukemia. We are grateful for the resources provided by UT, which have been instrumental in advancing our research endeavors.
